Parents

• David Weems (1706–1779)
• Esther Hill (1717–1776)

Spouses

• Rachel Morris
• Anne Ewell "Nancy" (1770–1813)
• Ann Taylor

Siblings

• James Richard Weems (1740–1780)
• Ann Weems (1742–1744)
• Williamina Weems -1 (1744–1744)
• Susannah Weems (1745–1805)
• David Weems Jr. -1 (1747–1747)
• David Weems Jr. -2 (1748–1750)
• David Weems Jr. -3 (1750–1750)
• David Lock Weems Jr. -4 (1751–1820)
• Williamina Weems -2 (1754–1783)
• Ester Weems (1756–1756)
• Mason Loch "Parson" Weems (1759–1825)

Children

• William Morris Weems (1785–?)
• Elijah Weems (1787–1836)
• Sophie Weems
• James Ewell Weems
• Marianna Ewell Weems (1798–1839)
• David Locke Weems
• Anne Weems

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